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Which enzyme releases AA from cell membrane phospholipids?

  1. Phospholipase A2

  2. Lipooxygenase

  3. Cytochrome P450

  4. Elongase

The correct answer is: Phospholipase A2

Phospholipase A2 is the enzyme responsible for releasing AA (arachidonic acid) from cell membrane phospholipids. This enzyme is specifically designed to break down phospholipids, which are found in cell membranes. The other options are not involved in this process and are incorrect. Lipooxygenase is involved in converting AA into inflammatory mediators, not releasing it from cell membranes. Cytochrome P450 plays a role in drug metabolism and detoxification, but not in releasing AA from phospholipids. Elongase is an enzyme involved in fatty acid elongation, not phospholipid breakdown. So, the correct answer is A, phospholipase A2.